painful bowel movements
Bleeding around the anus
Severe Pain during your Bowel Movements?  
anal pain trial
Itching around the anus
I think I may have an anal fissure

An anal fissure is a break or tear in the tissue of the anus. This condition can occur in men and women of all ages. The pain associated with anal fissures most often occurs during a bowel movement and frequently lasts for one to two hours afterwards.

Doctors would like to talk with you about a medical research study for anal fissures, a common medical condition that causes sharp or burning pain, bleeding and itching around the anus.

How may I qualify for the APT study?

To be eligible for this study, you must:
  • Be between the ages of 18 and 75 years
  • Have an anal fissure for at least 6 weeks prior to the study. Symptoms may include:
    • Severe pain during and after a bowel movement
    • Bleeding around the anus following a bowel movement
    • Itching around the anus

    The investigational ointment being evaluated in the APT study is called Cellegesic. Cellegesic is a nitroglycerin ointment and is approved in the United Kingdom, Australia and other European countries, under the name Rectogesic®, for relieving pain associated with chronic anal fissures. It is not approved in the United States, Argentina, Brazil, Colombia, or Mexico.

Study participants will receive study-related medical evaluations and the investigational ointment at no cost. Reimbursement for time and travel will also be provided.

Scroll down for a list of participating sites in the United States, Argentina and Brazil. This list is regularly updated. If you do not find a site near you, please check back soon.

For more information about this study and clinical research, download the anal pain trial study brochure (Adobe Acrobat file, 540 KB) or view the study brochure in HTML.

Listing of study sites by country:

 United States
 
Arizona
Adobe Gastroenterology Research, LLC
2585 North Wyatt Dr.
Tucson, AZ 85712
(520) 318-1236

California
Helping Hands Clinical Trials
2621 S Bristol
Suite 307
Santa Ana, California 9270
714-918-3070

1211 West La Palma Ave.
Suite 602
Anaheim, CA 92801
714-774-7777

3808 Riverside Drive
Suite 400
Burbank, CA 91505
818-558-7555 or 877-WELL-DAY

California Pacific Medical Center
2340 Clay St.
Suite 325
San Francisco, CA 94115
415-600-1368

Florida
3633 Little Road
New Port Richey, FL 34655
727-835-3261

4284 Nelson Avenue
Marianna, FL 32446
850-482-5802

Kentucky
354 Waller Avenue
Lexington, KY 40504
(859) 225-5672

Louisiana
611 Grammont Street
Monroe, LA 71201
318-807-0819

3217 Mabel St.
Shreveport, LA 71103
(318) 525-3226

Maryland
621 Ridgely Ave,
Suite 201
Annapolis, MD 21401
410-224-4887 EXT 444

Chevy Chase Clinical Research
5530 Wisconsin Ave
Suite 820
Chevy Chase, MD 20815
301-652-5520

Michigan
William Beaumont Hospital
3811 W. 13 Mile Road
Suite 501
Royal Oak, MI 48073
(248) 551-7930

Mississippi
501 Marshall Street
Suite 205
Jackson, MS 39202
601-714-3261

Gastrointestinal Associates
1421 North State Street
Suite 203
Jackson, MS 39202
601-355-1234
New Jersey
3205 Fire Rd.
Egg Harbor Township, NJ 08234
(609) 407-1220 x 110

New York
1000 Northern Blvd.
Suite 160
Great Neck, NY 11021
(516) 466-2340

North Carolina
Charlotte Clinical Research
330 Billingsley Road
Suite 103
Charlotte, NC 28211
(704) 362-1442

3100 Blue Ridge Road
Suite 200
Raleigh, NC 27612
919-781-2514

1901 South Hawthorne Road
Suite 306
Winston-Salem, NC 27103
336-768-8062

Ohio
9500 Euclid Avenue
Department of Colorectal Surgery Research- Desk A30
Cleveland, OH 44195
216-445-8665

Consultants for Clinical Research, Inc.
2925 Vernon Place
Suite 200
Cincinnati, OH 45219
(513) 872-4549

Oregon
1501 North East Medical Center Drive
Clinical Research Department
Bend, OR 97701
1-877-692-8338 option 2

Pennsylvania
Milton S. Hershey Medical Center
500 University Dr.
Hershey, PA 17033
(717) 531-8496

Tennessee
8000 Wolf River Blvd.
Suite 200
Germantown TN 38138
901-747-3630 EXT 347

Texas
Scott & White Memorial Hospital
2401 S. 31st Street
Temple, TX 76508
254-724-1769

Virginia
112 Gainsborough Square
Suite 200
Chesapeake, VA 23320
757-547-0798 EXT 131

Argentina
Brazil
Colombia
Mexico

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